Semantics Relevance

2 new COVID variants called 'FLiRT'are spreading in the U.S. ...


Logical Analysis Report (click to view);
Knowledge Map (click to view)
*Knowledge Map Navigation: Spatial co-ordinations are initially random, and will automatically re-arrange to minimize complexity based on distance between relationships. Mouse down and drag to pan. Right click on the strategic diagram toggles between motion and stationary. Hover over abstract node (orange) to view abstractions. Hover over leaf node to view corresponding narrative. Left click on the leaf node expands the narrative to view full text.

Knowledge Diagram Navigation:

Spatial co-ordinations are initially random, and will automatically re-arrange to minimize complexity based on distance between relationships. Mouse down and drag to pan. Right click on the strategic diagram toggles between motion and stationary. Hover over abstract node (orange) to view abstractions. Hover over leaf node to view corresponding narrative. Left click on the leaf node expands the narrative to view full text.

Narrative Analysis - Report

Key Focus

  • According to the CDC, the type and severity of symptoms a person experiences usually depend more on a person's underlying health and immunity rather than the variant that caused the infection.. . Similar to JN.1 and other omicron subvariants, the FLiRT variants seem to be causing milder infections, says Schaffer. ...
  • Only time and more data will tell, the experts note.. . Laboratory studies suggest that KP.2 is mutated enough such that current vaccines and immunity from prior infection will only provide partial protection, says Schaffner. ...
  • What are the symptoms of the FLiRT variants. Are vaccines still effective. We spoke to experts to learn more.. . What are the FLIRT variants. ...
  • No momentum supporting factor found

    Challenge supporting factors

  • (variants,infection)
  • (flirt,infection)
  • (flirt,subvariants,infection)
  • (variants,experts,flirt,infection)
  • (variants,experts,infection)
  • (variants,flirt,infection)
  • (variants,flirt,vaccines)
  • (variants,experts,flirt,mutated)
  • (variants,experts,mutated)
  • (variants,flirt,mutated)
  • (variants,experts,flirt,laboratory)
  • (variants,experts,laboratory)
  • (variants,flirt,laboratory)
  • (flirt,subvariants,health)
  • (variants,flirt,health)
  • Work-in-progress supporting factors

  • (variants,flirt,subvariants)
  • (variants,flirt,omicron)
  • (variants,proportion)
  • (flirt,subvariants,virulent)
  • (flirt,virulent)
  • (variants,flirt,virulent)
  • (variants,virulent)
  • (flirt,vaccines)
  • (variants,experts,flirt,vaccines)
  • (variants,experts,vaccines)
  • (variants,flirt,vaccines)
  • (variants,vaccines)
  • (variants,subvariants)
  • (flirt,schaffer)
  • (flirt,subvariants,schaffer)

  • Time PeriodChallengeMomentumWIP
    Report45.48 0.00 54.53

    High Level Abstraction (HLA) combined

    High Level Abstraction (HLA)Report
    (1) (variants,infection)100.00
    (2) (variants,flirt,vaccines)90.85
    (3) (variants,flirt,subvariants)88.36
    (4) (variants,flirt,omicron)74.64
    (5) (variants,proportion)54.68
    (6) (flirt,infection)54.47
    (7) (flirt,subvariants,infection)53.64
    (8) (variants,experts,flirt,infection)53.22
    (9) (variants,experts,infection)51.35
    (10) (variants,flirt,infection)50.52
    (11) (flirt,subvariants,virulent)49.48
    (12) (flirt,virulent)49.27
    (13) (variants,flirt,virulent)49.06
    (14) (variants,virulent)48.65
    (15) (flirt,vaccines)48.44
    (16) (variants,experts,flirt,vaccines)47.19
    (17) (variants,experts,vaccines)46.36
    (18) (variants,vaccines)44.70
    (19) (variants,subvariants)43.24
    (20) (flirt,schaffer)43.04
    (21) (flirt,subvariants,schaffer)42.20
    (22) (variants,flirt,schaffer)41.37
    (23) (variants,schaffer)40.96
    (24) (variants,experts,flirt,population)40.12
    (25) (variants,experts,population)39.29
    (26) (variants,flirt,population)38.88
    (27) (variants,population)38.46
    (28) (flirt,subvariants,omicron)38.25
    (29) (variants,omicron)36.59
    (30) (variants,experts,flirt,mutated)35.97
    (31) (variants,experts,mutated)35.14
    (32) (flirt,virus)34.93
    (33) (variants,flirt,mutated)34.93
    (34) (flirt,subvariants,milder)34.72
    (35) (variants,flirt,milder)34.10
    (36) (variants,experts,flirt,laboratory)33.68
    (37) (variants,experts,laboratory)32.64
    (38) (variants,flirt,laboratory)32.43
    (39) (flirt,subvariants,health)32.22
    (40) (variants,flirt,health)31.60
    (41) (pekosz,variants,proportion)31.19
    (42) (variants,experts,proportion)30.77
    (43) (pekosz,variants,increasing)30.15
    (44) (variants,experts,increasing)29.94
    (45) (pekosz,variants,decreasing)29.52
    (46) (variants,experts,decreasing)29.31
    (47) (pekosz,variants,advantage)29.11
    (48) (variants,experts,advantage)28.90
    (49) (variants,vanderbilt_university_medical_center)28.69
    (50) (variants,professor)28.48
    (51) (flirt,cdc,virus)26.61
    (52) (flirt,cdc,variants)24.53
    (53) (flirt,cdc,vaccine-induced)22.66
    (54) (flirt,vaccine-induced)21.83
    (55) (flirt,cdc,sars-cov-2)20.79
    (56) (flirt,cdc,population)19.13
    (57) (flirt,cdc,infection)17.26
    (58) (flirt,cdc,immune)14.97
    (59) (flirt,cdc,health)13.31
    (60) (flirt,cdc,fades)11.02
    (61) (flirt,cdc,antibodies)10.81
    (62) (flirt,strains)9.36
    (63) (flirt,subvariants,evidence)8.52
    (64) (flirt,subvariants,disease)7.90
    (65) (flirt,subvariants,cdc)6.24
    (66) (flirt,summertime)4.99
    (67) (flirt,spending)4.37
    (68) (covid-19,fever-free)4.16
    (69) (pekosz,proportion)3.95
    (70) (pekosz,virus)3.53
    (71) (pekosz,variants,experts)3.12
    (72) (pekosz,pre-existing)2.91
    (73) (pekosz,positivity)2.70
    (74) (pekosz,population)2.49
    (75) (pekosz,experts)2.49
    (76) (pekosz,mutations)2.29
    (77) (pekosz,mid-january)2.08
    (78) (pekosz,increasing)1.87
    (79) (pekosz,evades)0.62
    (80) (pekosz,decreasing)0.42

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    Supporting narratives:

    Please refer to knowledge diagram for a complete set of supporting narratives.

    • challenge - Back to HLA
      • Laboratory studies suggest that KP.2 is mutated enough such that current vaccines and immunity from prior infection will only provide partial protection, says Schaffner. ...
      • High Level Abstractions:
        • (flirt,infection)
        • (variants,flirt,infection)
        • (variants,infection)
        • (variants,experts,flirt,infection)
        • (variants,experts,infection)
        • Inferred entity relationships (8)
        • (experts,flirt,population,variants) [inferred]
        • (infection,variants) [inferred]
        • (experts,flirt,mutated,variants) [inferred]
        • (flirt,infection) [inferred]
        • (experts,flirt,laboratory,variants) [inferred]
        • (flirt,infection,variants) [inferred]
        • (experts,flirt,vaccines,variants) [inferred]
        • (flirt,infection,subvariants) [inferred]

    • challenge - Back to HLA
      • According to the CDC, the type and severity of symptoms a person experiences usually depend more on a person's underlying health and immunity rather than the variant that caused the infection.. . Similar to JN.1 and other omicron subvariants, the FLiRT variants seem to be causing milder infections, says Schaffer. ...
      • High Level Abstractions:
        • (flirt,subvariants,health)
        • (flirt,subvariants,infection)
        • (variants,infection)
        • (variants,flirt,health)
        • Inferred entity relationships (4)
        • (flirt,infection) [inferred]
        • (flirt,health,subvariants) [inferred]
        • (flirt,infection,variants) [inferred]
        • (flirt,health,variants) [inferred]

    • challenge - Back to HLA
      • Only time and more data will tell, the experts note.. . Laboratory studies suggest that KP.2 is mutated enough such that current vaccines and immunity from prior infection will only provide partial protection, says Schaffner. ...
      • High Level Abstractions:
        • (variants,flirt,vaccines)
        • Inferred entity relationships (2)
        • (flirt,vaccines) [inferred]
        • (vaccines,variants) [inferred]

    • challenge - Back to HLA
      • Low vaccination rates and waning immunity create a vulnerable population, which may allow the FLiRT variants to take hold. Only time and more data will tell, the experts note.. . Laboratory studies suggest that KP.2 is mutated enough such that current vaccines and immunity from prior infection will only provide partial protection, says Schaffner ...
      • High Level Abstractions:
        • (variants,experts,flirt,mutated)
        • (variants,experts,mutated)
        • (variants,flirt,mutated)
        • (variants,experts,flirt,laboratory)
        • (variants,experts,laboratory)
        • (variants,flirt,laboratory)
        • Inferred entity relationships (7)
        • (experts,flirt,population,variants) [inferred]
        • (flirt,laboratory,variants) [inferred]
        • (experts,flirt,mutated,variants) [inferred]
        • (experts,flirt,laboratory,variants) [inferred]
        • (experts,flirt,vaccines,variants) [inferred]
        • (flirt,mutated,variants) [inferred]
        • (experts,flirt,infection,variants) [inferred]

    • challenge - Back to HLA
      • have natural or vaccine-induced antibodies against the the SARS-CoV-2 virus, per the CDC, but this immune protection fades over time.. . Low vaccination rates and waning immunity create a vulnerable population, which may allow the FLiRT variants to take hold ...
      • High Level Abstractions:
        • (flirt,cdc,fades)
        • (flirt,virus)
        • (flirt,cdc,virus)
        • (flirt,cdc,sars-cov-2)
        • (flirt,cdc,immune)
        • Inferred entity relationships (10)
        • (cdc,flirt,vaccine-induced) [inferred]
        • (cdc,flirt,subvariants) [inferred]
        • (cdc,flirt,infection) [inferred]
        • (cdc,flirt,immune) [inferred]
        • (cdc,flirt,sars-cov-2) [inferred]
        • (cdc,flirt,health) [inferred]
        • (cdc,flirt,virus) [inferred]
        • (cdc,flirt,population) [inferred]
        • (flirt,virus) [inferred]
        • (cdc,flirt,variants) [inferred]

    • challenge - Back to HLA
      • have natural or vaccine-induced antibodies against the the SARS-CoV-2 virus, per the CDC, but this immune protection fades over time.. . Low vaccination rates and waning immunity create a vulnerable population, which may allow the FLiRT variants to take hold. ...
      • High Level Abstractions:
        • (flirt,cdc,population)
        • Inferred entity relationships (9)
        • (cdc,flirt,vaccine-induced) [inferred]
        • (cdc,flirt,health) [inferred]
        • (cdc,flirt,subvariants) [inferred]
        • (cdc,flirt,infection) [inferred]
        • (cdc,flirt,immune) [inferred]
        • (cdc,flirt,virus) [inferred]
        • (cdc,flirt,variants) [inferred]
        • (cdc,flirt,sars-cov-2) [inferred]
        • (flirt,population,variants) [inferred]

    • challenge - Back to HLA
      • According to the CDC, the type and severity of symptoms a person experiences usually depend more on a person's underlying health and immunity rather than the variant that caused the infection. ...
      • High Level Abstractions:
        • (flirt,cdc,infection)
        • (flirt,cdc,health)
        • (flirt,subvariants,cdc)
        • Inferred entity relationships (16)
        • (cdc,flirt,vaccine-induced) [inferred]
        • (cdc,flirt,subvariants) [inferred]
        • (cdc,flirt,infection) [inferred]
        • (cdc,flirt,immune) [inferred]
        • (cdc,flirt,sars-cov-2) [inferred]
        • (flirt,infection) [inferred]
        • (cdc,flirt,health) [inferred]
        • (flirt,subvariants,variants) [inferred]
        • (flirt,health,subvariants) [inferred]
        • (flirt,subvariants,virulent) [inferred]
        • (flirt,infection,variants) [inferred]
        • (cdc,flirt,virus) [inferred]
        • (cdc,flirt,population) [inferred]
        • (cdc,flirt,variants) [inferred]
        • (flirt,infection,subvariants) [inferred]
        • (flirt,health,variants) [inferred]

    • challenge - Back to HLA
      • We're probably not at the stage yet where we'll see COVID go away completely at any time of the year," says Pekosz.. . Test positivity, which is an early indicator of case levels, is at 3% as of April 20, down 0.4% from the previous week and a sharp decline from around 12% in mid-January, per the CDC ...
      • High Level Abstractions:
        • (pekosz,positivity)

    • challenge - Back to HLA
      • Test positivity, which is an early indicator of case levels, is at 3% as of April 20, down 0.4% from the previous week and a sharp decline from around 12% in mid-January, per the CDC. ...
      • High Level Abstractions:
        • (pekosz,mid-january)

    • WIP - Back to HLA
      • William Schaffner, professor of infectious diseases at Vanderbilt University Medical Center, tells TODAY.com.. . The proportion of cases caused by KP.2 is increasing while the proportion caused by other variants is decreasing, which suggests KP.2 has features that give it an advantage, the experts note ...
      • High Level Abstractions:
        • (variants,proportion)
        • (variants,vanderbilt_university_medical_center)
        • (variants,professor)

    • WIP - Back to HLA
      • Similar to JN.1 and other omicron subvariants, the FLiRT variants seem to be causing milder infections, says Schaffer.. . "There's no evidence now that makes us think KP.2 is more virulent or more able to cause severe disease than the prior variants," says Ko. ...
      • High Level Abstractions:
        • (variants,flirt,virulent)
        • (flirt,subvariants,virulent)
        • (flirt,virulent)
        • (variants,virulent)
        • Inferred entity relationships (2)
        • (flirt,subvariants,variants) [inferred]
        • (variants,virulent) [inferred]

    • WIP - Back to HLA
      • What are the symptoms of the FLiRT variants. Are vaccines still effective. We spoke to experts to learn more.. . What are the FLIRT variants. ...
      • High Level Abstractions:
        • (flirt,vaccines)
        • (variants,vaccines)
        • (variants,flirt,vaccines)
        • (variants,experts,vaccines)
        • (variants,experts,flirt,vaccines)
        • Inferred entity relationships (7)
        • (experts,flirt,population,variants) [inferred]
        • (flirt,vaccines,variants) [inferred]
        • (experts,flirt,mutated,variants) [inferred]
        • (flirt,vaccines) [inferred]
        • (experts,flirt,laboratory,variants) [inferred]
        • (vaccines,variants) [inferred]
        • (experts,flirt,infection,variants) [inferred]

    • WIP - Back to HLA
      • "The FLiRT variants are probably not going to create very distinctive symptoms. It looks at the moment to follow the other subvariants," says Schaffner. ...
      • High Level Abstractions:
        • (variants,subvariants)
        • (variants,flirt,subvariants)
        • Inferred entity relationships (2)
        • (flirt,subvariants,virulent) [inferred]
        • (subvariants,variants) [inferred]

    • WIP - Back to HLA
      • According to the CDC, the type and severity of symptoms a person experiences usually depend more on a person's underlying health and immunity rather than the variant that caused the infection.. . Similar to JN.1 and other omicron subvariants, the FLiRT variants seem to be causing milder infections, says Schaffer.. . "There's no evidence now that makes us think KP.2 is more virulent or more able to cause severe disease than the prior variants," says Ko ...
      • High Level Abstractions:
        • (flirt,subvariants,omicron)
        • (variants,flirt,omicron)
        • (variants,flirt,subvariants)
        • (flirt,subvariants,milder)
        • (variants,flirt,milder)
        • Inferred entity relationships (7)
        • (flirt,milder,subvariants) [inferred]
        • (flirt,milder,variants) [inferred]
        • (flirt,subvariants,virulent) [inferred]
        • (flirt,omicron,variants) [inferred]
        • (flirt,omicron,subvariants) [inferred]
        • (omicron,variants) [inferred]
        • (subvariants,variants) [inferred]

    • WIP - Back to HLA
      • Similar to JN.1 and other omicron subvariants, the FLiRT variants seem to be causing milder infections, says Schaffer.. . "There's no evidence now that makes us think KP.2 is more virulent or more able to cause severe disease than the prior variants," says Ko ...
      • High Level Abstractions:
        • (flirt,subvariants,schaffer)
        • (flirt,subvariants,evidence)
        • (flirt,schaffer)
        • (variants,flirt,schaffer)
        • (variants,schaffer)
        • Inferred entity relationships (6)
        • (flirt,schaffer,subvariants) [inferred]
        • (flirt,subvariants,variants) [inferred]
        • (flirt,subvariants,virulent) [inferred]
        • (schaffer,variants) [inferred]
        • (flirt,schaffer) [inferred]
        • (flirt,schaffer,variants) [inferred]

    • WIP - Back to HLA
      • Low vaccination rates and waning immunity create a vulnerable population, which may allow the FLiRT variants to take hold. Only time and more data will tell, the experts note. ...
      • High Level Abstractions:
        • (variants,experts,flirt,population)
        • (variants,experts,population)
        • (variants,flirt,population)
        • (variants,population)
        • Inferred entity relationships (6)
        • (experts,flirt,laboratory,variants) [inferred]
        • (experts,flirt,vaccines,variants) [inferred]
        • (population,variants) [inferred]
        • (flirt,population,variants) [inferred]
        • (experts,flirt,infection,variants) [inferred]
        • (experts,flirt,mutated,variants) [inferred]

    • WIP - Back to HLA
      • over the last year - JN.1, HV.1, EG.5 aka Eris, and XBB.1.16 or Arcturus - the FLiRT variants part of the omicron family.. . The emergence of KP.2 and other FLiRT variants is the "same old story," Andrew Pekosz, Ph.D., virologist at Johns Hopkins University, tells TODAY.com ...
      • High Level Abstractions:
        • (variants,flirt,omicron)
        • (variants,omicron)
        • Inferred entity relationships (2)
        • (flirt,omicron,subvariants) [inferred]
        • (omicron,variants) [inferred]

    • WIP - Back to HLA
      • The proportion of cases caused by KP.2 is increasing while the proportion caused by other variants is decreasing, which suggests KP.2 has features that give it an advantage, the experts note ...
      • High Level Abstractions:
        • (variants,experts,proportion)
        • (pekosz,variants,proportion)
        • (pekosz,variants,increasing)
        • (variants,experts,increasing)
        • Inferred entity relationships (3)
        • (increasing,pekosz) [inferred]
        • (pekosz,proportion) [inferred]
        • (proportion,variants) [inferred]

    • WIP - Back to HLA
      • The proportion of cases caused by KP.2 is increasing while the proportion caused by other variants is decreasing, which suggests KP.2 has features that give it an advantage, the experts note. ...
      • High Level Abstractions:
        • (pekosz,variants,advantage)
        • (pekosz,variants,decreasing)
        • (pekosz,variants,experts)
        • (pekosz,increasing)
        • (pekosz,proportion)
        • (variants,experts,decreasing)
        • (variants,experts,advantage)
        • Inferred entity relationships (4)
        • (experts,pekosz) [inferred]
        • (pekosz,proportion,variants) [inferred]
        • (decreasing,pekosz) [inferred]
        • (increasing,pekosz,variants) [inferred]

    • WIP - Back to HLA
      • Low vaccination rates and waning immunity create a vulnerable population, which may allow the FLiRT variants to take hold. ...
      • High Level Abstractions:
        • (flirt,cdc,variants)
        • Inferred entity relationships (9)
        • (cdc,flirt,vaccine-induced) [inferred]
        • (cdc,flirt,health) [inferred]
        • (cdc,flirt,subvariants) [inferred]
        • (flirt,variants,virulent) [inferred]
        • (cdc,flirt,infection) [inferred]
        • (cdc,flirt,immune) [inferred]
        • (cdc,flirt,virus) [inferred]
        • (cdc,flirt,population) [inferred]
        • (cdc,flirt,sars-cov-2) [inferred]

    • WIP - Back to HLA
      • have natural or vaccine-induced antibodies against the the SARS-CoV-2 virus, per the CDC, but this immune protection fades over time. ...
      • High Level Abstractions:
        • (flirt,cdc,antibodies)
        • (flirt,cdc,vaccine-induced)
        • (flirt,vaccine-induced)
        • Inferred entity relationships (10)
        • (cdc,flirt,vaccine-induced) [inferred]
        • (cdc,flirt,subvariants) [inferred]
        • (cdc,flirt,infection) [inferred]
        • (cdc,flirt,immune) [inferred]
        • (flirt,vaccine-induced) [inferred]
        • (cdc,flirt,sars-cov-2) [inferred]
        • (cdc,flirt,health) [inferred]
        • (cdc,flirt,virus) [inferred]
        • (cdc,flirt,population) [inferred]
        • (cdc,flirt,variants) [inferred]

    • WIP - Back to HLA
      • Second, many people have immunity from recently being infected with the FLiRT variant predecessor JN.1. Last, during the summertime, people are spending less time indoors, which allows the virus fewer opportunities to spread. ...
      • High Level Abstractions:
        • (flirt,spending)
        • (flirt,virus)

    • WIP - Back to HLA
      • "There's no evidence now that makes us think KP.2 is more virulent or more able to cause severe disease than the prior variants," says Ko. ...
      • High Level Abstractions:
        • (flirt,subvariants,disease)
        • Inferred entity relationships (2)
        • (flirt,subvariants,variants) [inferred]
        • (flirt,subvariants,virulent) [inferred]

    • WIP - Back to HLA
      • Second, many people have immunity from recently being infected with the FLiRT variant predecessor JN.1. Last, during the summertime, people are spending less time indoors, which allows the virus fewer opportunities to spread ...
      • High Level Abstractions:
        • (flirt,summertime)

    • WIP - Back to HLA
      • First, KP.2 is not a highly divergent variant - in other words, it doesn't have a very large number of new mutations that differentiate it from other strains. Second, many people have immunity from recently being infected with the FLiRT variant predecessor JN.1 ...
      • High Level Abstractions:
        • (flirt,strains)

    • WIP - Back to HLA
      • It is still too early to tell whether the symptoms of KP.2 and other FLiRT variants are different from previous strains.. . "The FLiRT variants are probably not going to create very distinctive symptoms. ...
      • High Level Abstractions:
        • (flirt,strains)

    • WIP - Back to HLA
      • Test for COVID-19 if you have symptoms or an exposure.. . Stay home when you are sick.. . Return to normal activities only after you have been fever-free and symptoms have been improving for at least 24 hours. ...
      • High Level Abstractions:
        • (covid-19,fever-free)

    • WIP - Back to HLA
      • "Except it has these two mutations. I think these two mutations together are making KP.2 a better virus in that it maintains its ability to transmit, but also now evades some of the pre-existing immunity in the population," says Pekosz ...
      • High Level Abstractions:
        • (pekosz,virus)

    • WIP - Back to HLA
      • I think these two mutations together are making KP.2 a better virus in that it maintains its ability to transmit, but also now evades some of the pre-existing immunity in the population," says Pekosz. ...
      • High Level Abstractions:
        • (pekosz,pre-existing)
        • (pekosz,population)
        • (pekosz,evades)

    • WIP - Back to HLA
      • KP.2 looks very similar to its parental strain JN.1, says Pekosz, which is highly contagious. "Except it has these two mutations. I think these two mutations together are making KP.2 a better virus in that it maintains its ability to transmit, but also now evades some of the pre-existing immunity in the population," says Pekosz ...
      • High Level Abstractions:
        • (pekosz,mutations)

    • WIP - Back to HLA
      • The proportion of cases caused by KP.2 is increasing while the proportion caused by other variants is decreasing, which suggests KP.2 has features that give it an advantage, the experts note.. . KP.2 looks very similar to its parental strain JN.1, says Pekosz, which is highly contagious ...
      • High Level Abstractions:
        • (pekosz,experts)
        • (pekosz,decreasing)
        • Inferred entity relationships (2)
        • (decreasing,pekosz,variants) [inferred]
        • (experts,pekosz,variants) [inferred]

    • WIP - Back to HLA
      • COVID-19 has caused summer waves in the past, the experts note, which are often smaller than the winter surges. "I don't think that we'll see any kind of massive surge in cases," says Pekosz. ...
      • High Level Abstractions:
        • (pekosz,experts)
        • Inferred entity relationships (1)
        • (experts,pekosz,variants) [inferred]